Happiness & Public Policy

The Quest for a Scientific Politics of Well-Being

An Epidemic of Misdiagnosis

In the post below I say I’m skeptical of numbers showing an explosion in rates of depression. Here, in part, is why… From yesterday’s New York Times.

About one in four people who appear to be depressed are in fact struggling with the normal mental fallout from a recent emotional blow, like a ruptured marriage, the loss of a job or the collapse of an investment, a new study suggests. To avoid unnecessary diagnoses and stigma, the standard definition of depression should be redrawn to specifically exclude such cases, the authors argue.

The study, appearing today in The Archives of General Psychiatry, is based on survey data from more than 8,000 Americans; it did not analyze the number of people who had been misdiagnosed.

Psychiatrists and other doctors who take careful medical histories do so precisely to rule out such life blows, as well as the effects of physical illnesses, before making a diagnosis of depression.

But the American Psychiatric Association’s diagnostic manual does not specifically exclude people experiencing deep but normal feelings of sadness, unless they are bereaved by the death of a loved one. And an increasing number of school districts and health clinics use simple depression checklists, which do not take context into account, the authors said.

“Larger and larger numbers of people are reporting symptoms on these checklists, and there’s no way to know whether we’re finding normal sadness responses or real depression,” said Jerome C. Wakefield, a professor of social work at New York University and the study’s lead author.

This is big. As I’ve pointed out before, the depression stats and the happiness stats seem to be in conflict. There has been a stable or shrinking percentage of the population in the bottom happiness category despite alleged huge increases in the incidence of depression. This creates a problem for researchers who lean hard on both sets of data, like Diener and Seligman do in their paper “Beyond Money.” Here’s the dialectic as I see it…

If the depression data is right, the happiness data must be broken for failing to detect any increase in the proportion of the population feeling unwell. You would then have to give up on using the happiness data as evidence that many people are not getting happier, since you’ve already established the unreliability of self-reportinng to track important changes in psychological well-being. Now, you could argue that depression and unhappiness are different and statistically unrelated things. But then you need to convince us which one is more important for well-being. If the depression numbers are right, and depression is a huge deal, but has no relationship to unhappiness, then perhaps self-reported happiness and unhappiness are not very relevant to well-being. But then you don’t get to skip back and forth from one set of data to the other, whenever it is convenient to your argument.

You could argue that the happiness data are right, in which case, you’ll have a problem with the depression data. Again, you could distinguish between unhappiness and depression, and argue that they could vary independently. But, again, you’ll have to take a stand on what matters for well-being. Or argue that they are both important, but incommensurable. Alternatively, you could argue that both sets of data have their problems. This is my view. In this case, for the reasons Wakefield and Horwitz lay out, I am more skeptical of the depression data than the happiness data, which I think is likely to be most accurate at picking up changes at the bottom, since bad feelings are more psychologically salient and available than good ones, and therefore more likely to be accurately reported.

My hunch: much depression is misdiagnosed for failing to distinguish between functional sadness and disordered malaise, as above. And much is more or less intentionally misdiagnosed in order to give non-depressed people legal, insurance-covered access to SSRI’s, as Wakefield and Horwitz describe elsewhere. Importantly, SSRI’s really do make people feel better. Since there are far fewer truly depressed people than we think there are, but prescriptions for SSRIs based on bad depression diagnoses continue to rise, increasing rates of diagnosed depression may actually correlate with an improvement in the average tone of experience. O Brave New World!

7 Comments so far

  1. Gloria April 6th, 2007 10:25 am

    I am not surprised by this at all. When I was barely out of middle school, my parents decided I should see a therapist. She tried to convince me that I had all sorts of issues (AKA you seem depressed and then some and the only way for you to get past this is to pay me, because only I can make you better). Never mind the normal childhood - adolescent issues we all face.

    It’s a good thing I had enough sense to shrug her off. Otherwise, I would probably be in debt now.

    I just finished this book, How Doctors Think, by Dr. Groopman. It’s a good read. He talks about how doctors in the medical profession make misdiagnoses 20% of the time! These are medical doctors we’re talking about! So, when it comes to psychological issues, misdiagnoses must be even more common place.

  2. Michele Moore April 10th, 2007 12:14 pm

    GREAT posting, many thanks for your interesting insights!

    Look at the economic interests of the individuals and organizations conducting these studies. Profit motives clearly influence many of their claims.

    In an era of managed care, depression is an especially enticing industry for professionals treating psychological distress.

    The more accepted and generalized depression becomes, the more willing people and insurance companies will be to spend money to treat it.

    Economic interests drive much of this research and limits effective studies of happiness.

    Michele Moore
    http://HappinessBlog.com

  3. Sherri Leigh April 10th, 2007 8:03 pm

    As a society we are generally looking to label everything so we can “understand” it. Labels are often black or white, not shades of gray, so if it’s not happiness, it must be depression. We have to realize that sometimes it’s just unhappy.

    Sherri Leigh
    On a Lighter Note…

  4. John Gathercole April 17th, 2007 4:45 pm

    Interesting theory about increased prescription of SSRI’s actually leading to increased SWB. About a year ago I started taking melatonin for high blood pressure, and it improved my sleep and mood as well. I had always been an irritable person, but taking melatonin regularly made me more relaxed and content all around the clock, a difference noticed by my wife and my friends (it also lowered my blood pressure). The widespread idea that the happiness produced by drugs is somehow not “real” happiness is given the lie by my own experience, at least.

  5. Yennie June 11th, 2007 2:18 am

    Hm.. I see your point Will. I may mention that many people with actual depression do not immediately seek treatment (in fact the saying goes, many suffer in silence) so when they finally do seek treatment, the usual method is to treat with medication (SSRIs). It would seem that if people who wanted to feel better or to feel a better high would go seek something like oxytocin or vicodin and fake pain instead (which is more common). I suppose the real matter would be how many are actually being misdiagnosed (the numbers of people)

  6. Keith September 4th, 2007 6:33 pm

    I think you are making much of a simple sampling missmatch. The resolution of the data-sets is so different that they should not be compared in the way that you imply. Additionally, I think that depression may well be over-reported in the USA compared to other countries. Surveys of self-reported happiness are subject to sampling bias and probably underrepresent incidence of depression. The problem is technical rather than “a big deal”.

  7. David C Schupbach December 14th, 2007 3:58 pm

    Thank you very much for this article. This clears up some of my own confusion. As someone recovering from depression, it is sometimes hard to separate normal sadness from true depression.

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